週次 |
日期 |
單元主題 |
第1週 |
8/2 |
課程介紹 |
第2週 |
9/26 |
王愛玉
How to develop presentation skills |
第3週 |
10/3 |
PowerPoint show |
第4週 |
10/10 |
國慶日放假 |
第5週 |
10/17 |
劉毓欣
Processing-independent CRISPR RNAs limit natural transformation in Neisseria meningitidis (Mol Cell 50: 488-503, 2013)
|
第6週 |
10/24 |
(1) 馬蓁華 Bacteriophage genes that inactivate the CRISPR/Cas bacterial immune system (Nature 493: 429-432, 2013)
(2) 張宏宇 Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression
(Cell 152: 1173-1183, 2013)
|
第7週 |
10/31 |
(1) 蔡宗翰 CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes (Cell 154: 442-451, 2013)
(2) 林煜晟CRISPR/Cas9 systems targeting beta-globin and CCR5 genes have substantial off-target activity
(Nucl Acid Res doi:10.1093/nar/gkt714, 2013) |
第8週 |
11/07 |
演講 (待邀請) |
第9週 |
11/14 |
侯健睿 A pseudogene long-noncoding-RNA network regulates PTEN transcription and translation in human cells
(Nature Struct Mol Biol 20: 440-446, 2013) |
第10週 |
11/21 |
(1) 吳上豪 A SWI/SNF chromatin-remodeling complex acts in noncoding RNA-mediated transcriptional silencing
Mol Cell 49: 298-309, 2013
(2) 盧彥云 Long non-coding antisense RNA controls Uchl1 translation through an embedded SINEB2 repeat
(Nature 491: 454-457, 2012) |
第11週 |
11/28 |
(1) 潘妍卉 LncRNA loc285194 is a p53-regulated tumor suppressor (Nucl Acid Res 41: 4976-4987, 2013)
(2) 楊宗樺 Integrative genomic analyses reveal clinically relevant long noncoding RNAs in human cancer
(Nature Struct Mol Biol 20: 908-913, 2013) |
第12週 |
12/05 |
林延翰 Circular RNAs are abundant, conserved, and associated with ALU repeats
(RNA 19: 141-157, 2013) |
第13週 |
12/12 |
黃柏源 Circular RNAs are the predominant transcript isoform from hundreds of human genes in diverse cell types
(PLoS ONE 7: e30733, 2012) |
第14週 |
12/19 |
(1) 陳昱光 Circular RNAs are a large class of animal RNAs with regulatory potency (Nature 495: 333-338, 2013)
(2) 陳岳廷 Natural RNA circles function as efficient microRNA sponges (Nature 495 : 384-388, 2013) |
第15週 |
12/26 |
Discussion |